No subject
Mon Sep 28 15:09:14 CDT 2009
Here is my shot at a summary statement of points I might allude to in
an initial few minutes (no more than five) and be prepared to amplify
on if and when warranted during the discussion.
Major Premise: What the University is uniquely good at is taking the
long view, doing the fundamental research that precedes and underlies
deployment of technology in the "real world." The university has an
obligation to contribute the fruits of that research to the world,
but also not to permit itself to be diverted from its basic mission
by immediate societal needs. In that context, perhaps the university
can contribute to the fight against bioterrorism in four fundamental
ways, that are consistent with the universitys basic mission to
train students and produce fundamental new knowledge :
1. Doing research underlying the development of a new kind of
antimicrobial drugs, that will target specific gene products in
specific pathogens. These drugs are made necessary by the evolution
of microbial resistance to broad spectrum antibiotics, and the
corresponding potential ability of terrorists to launch attacks with
drug-resistant pathogens. However in the short term specific
antimicrobial drugs will not be developed by pharmaceutical
companies, because the size of the market in the near future relative
to the development costs strongly favors broad spectrum antibiotics.
So the basic research for specific antimicrobial drugs must take
place in the public sector, and research universities are an
excellent place for it.
2. Doing research underlying the development of specific, rapid,
and scalable diagnostic techniques for microbial infection. Specific
drugs will be useless without specific diagnosis, so this item is a
necessary corollary to item #1. Like item #1, this will not happen
in the private sector, as long as the pharmaceutical companies are
tied to an antimicrobial strategy utilizing broad-spectrum
antibiotics.
3. Doing research underlying the development of easily
deployable environmental sensors for microbes.
4. Bridging the gap between the university culture and the
law-enforcement culture in a way that assists in combating terrorism
without compromising university values in generating and
disseminating knowledge. Both law-enforcement officials and
university and university researchers need to be on the same page as
to what information should not be disseminated (for example, cookbook
recipes for weaponizing microbes) and what should be freely
disseminated (for example, knowledge about the molecular biology and
physiology of pathogens, which provides a critical foundation for
biomedical research).
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